JOURNAL OF EVIDENCE BASED MEDICINE AND HEALTHCARE

Table of Contents

2018 Month : February Volume : 5 Issue : 6 Page : 537-541

CORRELATION BETWEEN SERUM HSCRP AND CORONARY ARTERY DISEASE SEVERITY IN PATIENTS WITH ACUTE STEMI

Narendra Shankargouda Hiregoudar1, Basavaraj Devendrappa Baligar2, Varun Bhaktaraahalli Renukappa3, Vikram Ramshetty Rathod4

Corresponding Author:
Dr. Varun Bhaktaraahalli Renukappa,
#179, Vivek Hostel, KIMS, Campus, Hubli- 21.
E-mail: br.br.varun@gmail.com
DOI: 10.18410/jebmh/2018/109

ABSTRACT
BACKGROUND
CRP levels increase after acute myocardial infarction (AMI) but their changes in the process of an acute ischemic attack has been studied mainly in patients with non-ST elevation MI. It seems that elevated levels of circulating inflammatory markers, especially Highly Sensitive C-reactive protein (CRP), bear prognostic information and may contribute to the long-term risk stratification of patients with acute coronary syndromes.

MATERIALS AND METHODS
The study was conducted in ICCU of KIMS, Hubli on 68 patients presenting with acute STEMI, diagnosed on the basis of ECG findings. Serum hsCRP was measured in all patients at admission and all patients underwent coronary angiogram. The study aimed at correlating the severity of coronary artery disease with the hsCRP levels.
Type of study- Cross sectional. Sample size- 68 patients with acute STEMI.

RESULTS
Incidence of STEMI was higher in males in our study with a percentage of 75%. 25% of these patients had triple vessel disease. Patients with TVD had higher BMI, Higher hsCRP and LDL cholesterol when compared to patients with SVD.

CONCLUSION
Patients with STEMI having high HsCRP levels tend to have triple vessel disease. Also, it was found in the study that higher the BMI and LDL cholesterol, more likely that patient can have a triple vessel disease.

KEYWORDS
STEMI, hsCRP, Coronary Artery, Severity.