JOURNAL OF EVIDENCE BASED MEDICINE AND HEALTHCARE

Table of Contents

2018 Month : September Volume : 5 Issue : 36 Page : 2644-2650

A STUDY ON THE INFLUENCE OF ENVIRONMENTAL FACTORS IN RHEUMATOID ARTHRITIS

Satish Kumar1, UshaKulangara Aravind2

Corresponding Author:
Dr. Satish Kumar,
Research Scholar,
Advanced Centre of Environmental Studies and
Sustainable Development, Mahatma Gandhi University,
Kottayam, Kerala.
E-mail: profsatishkumar1970@gmail.com
DOI: 10.18410/jebmh/2018/543

ABSTRACT
BACKGROUND
Rheumatoid arthritis is a common rheumatological disorder of unknown cause. The development of rheumatological disorders like rheumatoid arthritis depends on the interaction between genetic background and number of environmental factors. Number of environmental factors have been implicated in the aetiology of rheumatic diseases which include infections like Epstein Bar Virus (EBV) Mycobacterium tuberculosis, Escherichia coli, Proteus mirabilis, and parvovirus B19. The other environmental factors include sunlight, cold climate, smoking, drugs and adjuvants, diet, exercise, occupation, radiation exposure, drinking water, psychological status, air pollution, chemicals, drugs, socioeconomic status, geographic location, hot and cold climate, occupation and alcohol.

MATERIALS AND METHODS
Cross sectional observational study. The sample selected was of 152 patients with rheumatoid arthritis fulfilling the ACR-EULAR 10 criteria. The tools used were clinical profile, 2010 ACR–EULAR 10 criteria, serology and acute phase reactants. The data was analyzed using SPSS-8 software.

RESULTS
In the study, most of the rheumatoid arthritis patients were females. In the study, the majority of the patients with rheumatoid arthritis resided in high ranges, were smokers and non-alcoholics. Rheumatoid arthritis is common in patients taking non-vegetarian diet, manual labours, those with low level of education and low socio-economic status. Most of the patients had aggravation of symptoms following exposure to cold and stress.

CONCLUSION
In the study, most of the rheumatoid arthritis patients were females. Environmental factors like smoking, alcoholism, diet, occupation, educational status, socioeconomic status, place of residence, climatic conditions and stress significantly influenced the occurrence and progression of symptoms in rheumatoid arthritis patients.

KEYWORDS
Rheumatoid Arthritis, Environmental Factors.