JOURNAL OF EVIDENCE BASED MEDICINE AND HEALTHCARE

Table of Contents

2019 Month : March Volume : 6 Issue : 13 Page : 1062-1065

EVALUATION OF LIVER DISEASES AMONG PATIENTS OF METABOLIC SYNDROME

Parimal Sarkar1, Subarna Bhattacharjee2

Corresponding Author:
Dr. Parimal Sarkar,
Assistant Professor,
Department of General Medicine,
Agartala Government Medical College,
Agartala, Tripura.
E-mail: drsarkaragt68@gmail.com
DOI: 10.18410/jebmh/2019/221

ABSTRACT
BACKGROUND
Several cross-sectional studies have reported on the prevalence of liver diseases among patients of metabolic syndrome. The aim of the study was to determine the prevalence of liver diseases among patients of metabolic syndrome.

METHODS
The study included 123 patients between 18-70 years of age, over a period of one & half year from January 2016 to June 2017. Anthropometric measurements like height, weight, waist & hip circumference, body mass index (BMI) were recorded. Biochemical tests included blood sugar (FBS & PPBS), lipid profile, LFT, viral markers & ultrasonography of whole abdomen were done to detect presence of liver diseases among patients of metabolic syndrome.

RESULTS
In this study group, 52.8% were males & 47.2 % were females. Most of the cases were overweight (51.2%). The prevalence of overall liver disease was 60.2 %. NAFLD was the most commonly observed liver disease (34.1%). It was followed by raised transaminase level (16.3%) & lastly NASH related cirrhosis (9.8%). Presence of dyslipidaemia (58.5%), hypercholesterolemia (73.0%), hypertriglyceridemia (85.1%) & low HDL-C (81%) were associated with liver disease.

CONCLUSION
A very high prevalence (60.2%) of liver disease was found in this study. Females were having higher prevalence of liver diseases than males. NAFLD was the most commonly observed liver disease. The proportion of NASH related cirrhosis & transaminasemia were marginally higher as compared to studies done in other parts of India.