JOURNAL OF EVIDENCE BASED MEDICINE AND HEALTHCARE

Table of Contents

2019 Month : April Volume : 6 Issue : 13 Page : 1074-1077

HISTOPATHOLOGICAL PROFILE OF PROSTATECTOMY SPECIMENS IN A TERTIARY HOSPITAL

Phuritshabam Pinky1, Vaskerjeet Konsam2, Alpana Laisom3, Athokpam Marina4, Ronal Singh Rajkumar5, Leishangthem Nabina6, Rajesh Singh Laishram7

Corresponding Author:
Dr. Rajesh Singh Laishram,
Department of Pathology,
Regional Institute of Medical Sciences,
Imphal West- 795004, Manipur.
E-mail: rajeshlaishr@gmail.com
DOI: 10.18410/jebmh/2019/224

ABSTRACT
BACKGROUND
Diseases of the prostate are common causes of morbidity and mortality in adult males. Benign prostatic hyperplasia is an extremely common disorder in men over the age of 50. Other frequently encountered diseases affecting the prostate are prostatitis, benign prostatic hyperplasia and prostatic cancer. Histopathological examination of prostate biopsy specimen is required to rule out the benign or malignant enlargement of prostate gland in older men. We wanted to study the histopathological patterns of prostatic diseases in prostatectomy specimens in RIMS Hospital.

METHODS
A 5-year cross sectional study was carried out between October 2007 and October 2012 in the Department of Pathology, RIMS. All the prostate specimens received for histopathological examination during the period of study were fixed, processed, and stained with Haematoxylin and Eosin, and examined for various prostatic lesions.

RESULTS
A total of 73 specimens were studied out of which 53 (72.60%) were Benign Prostatic Hyperplasia (BPH), making it the commonest lesion. 11 (15.07%) were BPH with nonspecific prostatitis while 2 (2.74%) were BPH with granulomatous prostatitis. BPH with Prostate Intraepithelial Neoplasia (PIN) was seen in 4 (5.48%) specimens. Only 3 (4.11%) were malignant. All the malignancies were Adenocarcinomas. The mean age of BPH cases was 69.2 years ranging from 54 to 80 years. The malignancies were seen in the seventh and the eight decades.

CONCLUSION
BPH accounted for about three-fourths (72.60%) of the prostatic tissue samples. Few pre-malignant (PIN) and malignant lesions were found. Other lesions like nonspecific prostatitis, granulomatous prostatitis were also encountered.