JOURNAL OF EVIDENCE BASED MEDICINE AND HEALTHCARE

Table of Contents

2019 Month : August Volume : 6 Issue : 31 Page : 2106-2112

A STUDY OF SPECTRUM OF HISTOPATHOLOGICAL LESIONS IN COLON IN A TERTIARY CARE CENTRE IN SOUTH KARNATAKA.

Mary Raju1, S. Teerthanath2

Corresponding Author:
Dr. Mary Raju,
Assistant Professor,
Department of Pathology,
Believers Church Medical College and Hospital,
Thiruvalla, Kerala.
E-mail: drmaryraju4@gmail.com
DOI: 10.18410/jebmh/2019/429

ABSTRACT
BACKGROUND
Histopathological study of colonoscopic biopsies is a well-established and cost-effective diagnostic test for evaluation of colonic lesions. It also contributes significantly to the pre-operate investigation of patients with colonic lesions .The main objective of the study is to scrutinize all colonoscopy biopsies and to study the Histopathology of colonic lesions and the spectrum of various colonic lesions and their prevalence in patients presenting to tertiary care hospital in South Karnataka. A total of 150 colonoscopic biopsies was studied in a 2-year period in the Department of Pathology, K. S. Hedge Medical Academy.

METHODS
Patients presenting with symptoms of pain abdomen, chronic altered bowel habits, haematochezia were examined by flexible colonoscopy after receiving consent from the patient. Biopsy specimen were mounted on a filter paper, fixed in formalin (10% solution of formaldehyde) and then processed. Sections of 3-4 ยต were mounted on a clean glass side and stained with haematoxylin and eosin (H&E) stain. Special stains like PAS, GMS, MTS, Ziehl Neelsen (ZN) etc., were used whenever indicated.

RESULTS
Age of the patients ranged from 3 years to 87 years with a mean age of 47.65 years. Majority of the patients were males (83 cases) with a male to female ratio of 1.23:1. Among 150 cases, 92 cases (61.3%) were non neoplastic lesions and 58 cases (38.7%) were neoplastic lesion. The ratio of non-neoplastic to neoplastic lesion was 1.58:1.

CONCLUSIONS
The incidence of colonic lesions is increasing in recent years with early onset of inflammatory bowel disease and colorectal neoplasm in relatively younger age group due to changing life style and dietary habits.

KEYWORDS
Colonoscopy, Neoplastic, Non-Neoplastic, IBD (Inflammatory Bowel Disease), Adenoma, Polyps, Adenocarcinoma