JOURNAL OF EVIDENCE BASED MEDICINE AND HEALTHCARE

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2020 Month : April Volume : 7 Issue : 18 Page : 904-908

Histopathological Study of Endometrial Biopsy in Cases of Infertility

Neelaba K. Mori1, Chandrika G. Algotar2, Kuldeepsinh D. Mori3

Corresponding Author:
Dr. Kuldeepsinh D. Mori,
Assistant Professor,
Department of Radio-diagnosis,
C.U. Shah Medical College and Hospital,
Surendra Nagar, Gujarat.
E-mail: drkuldeep2506@gmail.com

ABSTRACT
BACKGROUND
Reproduction is an essential aspect of marriage. Primary infertility is the inability to conceive after one year of unprotected coitus. Secondary infertility implies inability to conceive for 5 years of unprotected coitus after last conception including ectopic and recurrent abortions. The schedule of evaluation or investigations in infertility range from detailed clinical history, physical examination, basal body temperature, vaginal cytology, cervical mucus changes, endometrial biopsy, laparoscopy, ultrasonography, follicular study, hormone assays to immunoglobulin profile and new genetics. However, the most reliable method for diagnosing the cause of infertility in women remains the histopathological study of endometrial tissue.

METHODS
This is a prospective study carried out at a teaching hospital with the help of Department of Obstetrics and Gynaecology from 01/12/2014 to 01/08/2016. Patients who were reporting for infertility were the subjects of the study. The study included 150 cases of infertility.

RESULTS
Out of a total of 150 cases studied, 111 cases were primary infertility and 39 cases were secondary infertility with maximum incidence in the age group of 19-23 years and 29-33 years in primary and secondary infertility respectively with 2-13 years duration after marriage. Proliferative (anovulatory) endometrium is seen in 31 cases of primary and 15 cases of secondary infertility. Tuberculosis is seen in 2 cases primary infertility.

CONCLUSIONS
Primary infertility is more common than secondary infertility. It was observed that total duration of infertility in study group was 2-13 years. Anovulatory endometrium is the commonest cause of endometrium followed by tuberculous endometrium. Endometrial hyperplasia is the least common cause of infertility.

KEYWORDS
Infertility, Endometrial Biopsy, Anovulatory Cycle