Cataract, Presenile, Serum Tocopherol, Lipid Peroxidation, Reactive Oxygen Species, Antioxidant
AIM
In developing countries like India, cataracts evolve earlier in life and are three times more prevalent than developed countries. This study aims to determine significance of serum tocopherol level and its relation with early development of cataract.
MATERIAL AND METHOD
This study was carried out in the Departments of Ophthalmology and Biochemistry of Geetanjali Medical College and Hospital, Udaipur, Rajasthan during the period 2015-2016. For the study, 51 cases of presenile cataract and 51 presenile patients without cataract were included.
RESULT
There is significant difference in mean serum tocopherol level in presenile patients with and without cataract (P<0.001) and serum tocopherol level had no association with type of cataract, age and gender which leads to progression of cataract.
CONCLUSION
In this study population, serum tocopherol level was substantially lower in presenile cataract patients as compared with patients without cataract. Further long-term study is warranted to recommend monitoring of serum tocopherol level as it is inversely related to cataract.
