A Clinical Study on Malignant Neoplastic Thyroid Swellings

Abstract

Sumanth Mandava1 , Tarun Chowdary Gogineni2 , Vasu Reddy Challa3 , Karthik Santosh Appaji4 Sriphani Reddy Puvvala5 , T. Jaya Chandra6

BACKGROUND
More thyroid malignancy cases occur in women. FNAC (Fine Needle Aspiration 
Cytology) and histopathology play a key role in resolving this diagnostic challenge. 
A study was conducted to correlate the age, gender parameters with the clinical 
findings in thyroid malignancies by considering the histopathological examination 
(HPE) as the gold standard.
METHODS
It was a prospective study conducted in the department of Surgical Oncology, GSL 
Medical College, Rajahmundry, Malignant thyroid neoplasm individuals of any age, 
either gender who were fit thyroidectomy were included in the study. FNAC of the 
thyroid gland and lymph nodes was done. Data was analyzed using SPSS 21.0. Chi 
square test was used to find the statistical significance. P > 0.05 was considered to 
be statistically significant.
RESULTS
In this study, 52 HPE proven cases were studied, female male ratio was 5.5. Majority 
(28.8 %) of the study subjects were belong to 21 – 30 years. Majority (36.5 %) of 
the study volunteers had swelling for < 3 months and right side swelling was 
common. Papillary thyroid carcinoma (PCT) was common.
CONCLUSIONS
Thyroid carcinoma was common among females and PCT was common. FNAC 
contributed significantly to the preoperative investigation in thyroid swelling patients 
but despite its well-recognized value there are limitations to the technique.

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