Ishwar S. Hasabi1 , Gurusangappa S. Mudagall2
BACKGROUND There is enough evidence that the presence of diabetes increases the risk of clinical atherosclerotic disease from two-fold to three-fold, with coronary artery disease (CAD) as its chief sequelae. We wanted to study the type of vessels, number of vessels, severity of lesions involving coronary artery and its branches in patients with ACS and compare the involvement in diabetic and non-diabetic patients with ACS by Gensini scoring system. METHODS 144 Patients (72 diabetics and 72 nondiabetics) with acute coronary syndrome diagnosed by clinical examination, ECG and or/ cardiac enzyme levels, admitted in ICCU of KIMS Hospital, Hubli, and undergoing coronary angiography during the study period were included in the study as per the inclusion and exclusion criteria. Each patient was evaluated with history taking, clinical examination, and lab investigations (ECG, 2D-Echo, coronary angiography, HbA1c, lipid profile and renal function test). Based on angiographic findings, coronary artery disease severity was calculated using Gensini, and the data obtained was analysed by different statistical methods. RESULTS Out of 144 patients, ACS was commoner among males than females (72.9% vs. 27.1%) and age of presentation was earlier in males compared to females (53 yrs. vs. 58 yrs.). Multivessel disease was commoner in diabetics compared to nondiabetics (52.8% vs. 15.3%) and also mean Gensini score was higher in diabetics (45.2 vs. 19.2). CONCLUSIONS From this study we can conclude that diabetic patients with ACS have more severe coronary disease with respect to higher number of vessels involved, more severe occlusion and higher Gensini score and also severity increases with the duration of diabetes and poor glycaemic control.
