A COMPARATIVE STUDY OF BUPIVACAINE WITH MIDAZOLAM AND BUPIVACAINE ALONE IN BRACHIAL PLEXUS BLOCKADE

Abstract

Karthik Vannu Jagadish1, Mahalakshmi Sivapackiam2, Niranjan Kumar Anbazhakan3, Madhavakrishna Nandhi Mandalam Vasu4

BACKGROUND
Regional anaesthesia as the name implies is the blocking of peripheral nerve conduction in a reversible manner by using local anaesthetic agents, thereby one region of the body is made insensitive to pain and is devoid of reflex response to surgical stimuli. Regional anaesthesia offers many advantages over general anaesthesia1-5 for surgery on upper extremities, particularly in emergency operations. This study was designed as a prospective, randomised comparative study. After receiving the institutional ethical committee approval and informed consent, the patients were randomly allocated into two groups. Supraclavicular brachial plexus was performed via subclavian perivascular technique.
MATERIALS AND METHODS
Forty adult patients of both sexes in the age group of 20-60 years belonging to ASA I/II category and their weight ranging between 50-70 kgs posted for various types of upper limb surgeries at the Department of Plastic Surgery, Institute of Research and Rehabilitation of Hand, Government Stanley Hospital, formed the study group.
RESULTS
Onset time for both motor and sensory block was quicker in the bupivacaine with midazolam group. There was no significant difference between the groups in the time taken for completion of both motor and sensory blockade.
CONCLUSION
Midazolam can be considered as a safe additive to local anaesthetic solution for brachial plexus block.

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