K. Mydhili, T. Padma, S. Sreenivasa Rao
AIMS: This study was conducted to compare the intubating conditions between Rocuronium Bromide and Suxamethonium for endotracheal intubation in General anaesthesia. MATERIALS AND METHODS: In this prospective randomized controlled study 100 patients posted for different surgeries done under general anaesthesia were included in the study. The first group – Group I or Rocuronium (R) Group received Injection Rocuronium Bromide as the muscle relaxant. The second group- Group II or Suxamethonium (S) group received Injection Suxamethonium as the muscle relaxant. Descriptive statistics that included mean, standard deviation (SD), minimum and maximum values were calculated for each of the two study groups. The student ‘t’ test was used to determine whether significant differences were present in the different variables between the two study groups. The chi-square test was also used to determine significant differences in the various conditions between the groups. Significance for all statistical tests was pre-determined at a probability value (p-value) of 0.05 or less. Only those values which are significant have been mentioned. The patient belonging to Group I received Rocuronium 1 mg/kg as the muscle relaxant. The second group was designated as Group II or Suxamethonium group. These patients received Injection Suxamethonium 1.5mg/kg as the muscle relaxant. RESULTS: In our present study, we have used 3.3xED95 (1mg/kg) of Rocuronium bromide and 1.5 mg/kg of Suxamethonium as the intubating dose, produced good to excellent intubating conditions at 60 seconds as well as 90 seconds after administration. Intubating conditions following Suxamethonium (1.5 mg/kg) were comparable with those after Rocuronium. CONCLUSION: Rocuronium bromide in a dose of 1 mg/kg can be used as an alternative to Suxamethonium 1.5 mg/kg provided the airway has been carefully assessed and no difficulty is anticipated
