Shivwani1, Anjali Nadir Bhat2, Suresh Kotwal3, Kewal Kishore Thakur4
Hormonal changes associated with menopause alter serum lipid levels, which may play an important role in cardiac related disorders associated with menopause. We studied serum lipid profile changes in premenopausal, perimenopausal and postmenopausal females, so as to assess the differences in lipid levels amongst these three groups. The fasting blood samples were collected from 210 healthy volunteers who were allocated into three groups – Group I comprised of young healthy premenopausal females, Group II comprised of healthy perimenopausal females and Group III comprised of healthy postmenopausal females. Blood was collected after overnight fasting of 12 hours in all the subjects for estimation of serum levels of total cholesterol, high density lipoprotein, low density lipoprotein and triglycerides by enzymatic method. Statistically, significant increase was observed in total cholesterol and also in triglycerides and low density level in postmenopausal females as compared to premenopausal women. High density lipoprotein showed non-significant decrease in postmenopausal females
