Dipti Bania1, Jonly Hussain2, Geeta Barua3, Jayshri Devi4
INTRODUCTION
After menopause abnormal lipid levels and a relatively high incidence of coronary heart disease show a possible relationship among estrogens, normal lipid level and a relative immunity to CHD. A reduction of plasma HDL cholesterol may impair the normal clearance of cholesterol from arterial wall and thereby accelerate the development of atherosclerosis. In the study two groups of women were selected, one group of 100 cases between age group of 20-45 years and the other group of 100 cases between the age group of beyond 45 years who attained menopause. A total of 200 cases taken from various body mass index and various personal habits like smoking and alcohol consumption, food habits, etc. The investigation carried out was Total serum cholesterol, serum high density lipoproteins (HDL), Triglyceride, serum low density lipoproteins (LDL) and serum very low density lipoproteins (VLDL). These investigations were done in both the groups and collected data were analyzed statistically. The mean distribution of this parameter of lipid profile among the pre-menopausal subject is as follows-Total serum cholesterol-165.1±13.06mg%, HDL-57.35±8.05mg% TG-87.71±13.51mg%, LDL-9192±19.47mg% and VLDL-17.55±2.83mg%. The distribution of different parameters of lipid profile among the postmenopausal subjects are as follows- Total serum cholesterol 238.39±41.60mg%, HDL C-37.91±5.35mg% TG-149.61±33.15mg%, LDL-170.95±40.90, mg% VLDL-29.99±6.42mg%. On comparing both values of both the age group it was seen that total serum cholesterol, were increased in postmenopausal women significantly and there was a significant decrease in HDL C in post-menopausal state. In conclusion the study reflects menopause does have an unhealthy effect on serum cholesterol in women.
