Nidhi Kharb1, Praveen Kumar Malik2, Archana Rani3
BACKGROUND
Migraine is a common, disabling primary headache disorder. It is a constellation of symptoms like headache, nausea, vomiting, photophobia and other similar neurological dysfunction in varying admixtures. Since, migraine is a neurovascular disease, the highly reactive amino acid, homocysteine has been postulated to play a role in migraine pathophysiology.
MATERIALS AND METHODS
A total of 30 migraine patients participated in the present study including 22 females and 8 males. The study was directed towards the aim of finding out the prevalence of hyperhomocysteinemia in migraine patients, which came out to be 13.3% and other aim is to show association if any between homocysteine level and severity of migraine in which we found no direct relationship between serum homocysteine level and severity of migraine.
RESULTS
The study was carried out from May to June, 2017, among consecutive patient attending the OPD of Medicine and Psychiatry Department. In all, 30 migraine patients and 30 controls were interviewed during this phase. The result of the present study has been analysed and tabulated.
CONCLUSION
Prevalence of hyperhomocysteinemia in migraine was found to be 13.3% and there was no significant relation found between serum homocysteine levels and severity of migraine. Mean serum homocysteine level was found to be higher in migraine patient as compared to control, but the association did not came out to be statistically significant.
