Faias Karukappadath Siddique1, Arun Aravind2, Ashabi Mansoortheen3
BACKGROUND
Maintaining deep plane of anaesthesia to prevent haemodynamic fluctuation and
absolute immobility at the same time ensuring early and smooth recovery to
prevent bleeding and assessing vocal cord status are the challenges to the
anaesthesiologists in thyroid surgeries. Use of volatile anaesthetics with low
solubility and low blood gas partition coefficient are used for their haemodynamic
stability and faster emergence from anaesthesia in various surgeries under general
anaesthesia. we wanted to compare sevoflurane and desflurane in terms of
intraoperative haemodynamics, postoperative emergence and recovery
characteristics in thyroid surgeries of less than 2 hours duration.
METHODS
After getting institutional ethical committee approval, 70 patients belonging to
American Society of Anaesthesiologists (ASA), physical status I or II undergoing
elective thyroid surgery were randomly assigned to two groups to receive either 6
% Desflurane (group D ) or 2 % Sevoflurane (group S) for maintenance of general
anaesthesia along with 33 % oxygen with 67 % nitrous oxide. The intraoperative
heart rate, mean arterial pressure were recorded at 5 minute intervals and
recovery characteristics including times to extubation, first spontaneous motion,
response to painful pinch, recall of name, hand grip and PARS score ≥ 9 were
recorded in both groups.
RESULTS
There was no statistically significant difference (P > 0.05) in mean heart rate and
mean arterial pressure between group D and S and remained within 20 % of
baseline. The time to achieve a PARS ≥ 9 was earlier in the desflurane group and
it was statistically significant.
CONCLUSIONS
Desflurane and Sevoflurane based anaesthesia provides comparable intraoperative
haemodynamics whereas post-operative recovery was quicker in patients who
received Desflurane compared to Sevoflurane.
