A STUDY OF CORRELATION OF SERUM URIC ACID LEVELS IN DIABETES MELLITUS AND ITS SIGNIFICANCE IN PRE-SURGICAL EVALUATION

Abstract

Chakrapani Alavala1, Rajendra Prasad Kathula2

BACKGROUND
Raised serum uric acid has been
associated with a lot of diseases like hypertension, cardiovascular diseases, chronic kidney
disease, peripheral vascular diseases and metabolic disorders.
But the association of serum uric acid levels to that of
diabetes mellitus has not been successfully understood. A sincere
effort has been put in this study to find out the serum uric acid levels in normal individuals, pre diabetics and diabetics and
come to a conclusion on the correlation of serum uric acid in diabetes mellitus . The pre surgical evaluat ion of such conditions
forms an important basis for conducting surgeries. As stress levels in surgeries are supposed to be high which may further
worsen the diabetes or serum glucose levels may increase which may ultimately result in post surgical complica tions. So it
should be mandatory to check the serum uric acid lev els which may suggest the pre diabetes which may ultimately lead us to
prevent the post surgical complications.
METHOD
One hundred eighty people who visited the Department of Surgery were
selected.
The study included ninety males and ninety females and in each group
there were thirty non diabetic s , thirty pre diabetics
and thirty diabetics.
Pre
diabetics were considered as 110 to 125 mg/dL (6.1 mmol/L to 6.9 mmol /L) i.e. WHO criteria was f ollowed.
All the
subjects were aged between 40 60 years.
The correlations were made between the serum uric acid levels and se
rum fasting glucose, serum post prandial and
HbA1c.
RESULT
The results show a rise in the serum uric acid levels in the
pre diabetic and not so much in the non diabetics and the confirmed
diabetics.
CONCLUSION
The serum uric acid level measurements can be used as a powerful tool in identifying the pre
diabetic condition and help an
individual to make the necessary lifestyl e adjustments so that the progression of the diseases can be stopped or may be
infinitely delayed.

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