Manavalla Subrahmanyam1, Jakkula Kishore2, R. Mahalaxmi3
Xeroderma pigmentosa was first described by Hebra and Kaposis.[1] It’s a rare disorder transmitted by autosomal recessive manner.[2,3] Xeroderma characterized by dry, pigmented skin lesions resultant of severe sensitivity to UV radiation from sun exposure.[4,5,6] Main defect is inability to repair the DNA damage.[5] The prevalence is at 1: 1,000,000, the effects on skin is cumulative and irreversible.[1] There is 1000 fold increase in development of skin cancers, precancerous lesions of mouth and eye.[7,8] We are here presenting a case of xeroderma pigmentosa with skin cancer and its management and follow up
