AN UNUSUAL CASE OF AMEGAKARYOCYTIC THROMBOCYTOPENIA

Abstract

Anand L. Betdur1 , Ashok Bhagra2 , Krishna Tej C. H3 , Raja Ponnambalam4 , Somasekar D. S5

Acquired Amegakaryocytic thrombocytopenia (AAT) is a rare hematological disorder characterized by bleeding and severe thrombocytopenia with marked reduction or absence of megakaryocytes in the bone marrow. Prompt recognition of this condition is essential as the condition does not respond to steroids and immunoglobulins, instead responds better to immunosupressives like Azathioprine, Rituximab, Cyclosporine, Mycophenolate, Antithymocyte globulin alone or in combination with other drugs. We report such a rare case of AAT with rapid clinical remission by cyclosporine treatment.

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