Alneil Abdalla*, Elyasa Elfaki, Mariam Ibrahim, Omima Ibrahi, Tasamoh Eltayeb, Azaz Abdelgader, Aml Rhahammatalla, Nuha Abubaker, Altaf Taha, Alneil Hamza and Tarig Karar
Background
Acne is a skin inflammation that results from over activity of the oil gland as the base of specialized hair follicles. Elevated C - Reactive Protein (CRP) has been reported to occur in acne and many other dermatological conditions. These studies aimed to assess the levels of plasma lipid profile and CRP levels among Sudanese females with acne in Khartoum state.
Methods
This cross - sectional study was conducted from May to December 2018, involving fifty Sudanese females with acne their age ranged from 20 - 40 years, The levels of Total Cholesterol (TC), Triglyceride (TG), and High - Density Lipoprotein - Cholesterol (HDL - C) were measured by bio-system Bts -310, the Low - Density Lipoprotein - Cholesterol (LDL - C) was calculated using FriedWald equation, and CRP was measured by bio-system. Data analysis was carried out using SPSS version 21.
Results
The results revealed an increase in Body Mass Index (BMI), and CRP while there were normal levels of TC, TG, and HDL - C, and LDL - C in females with acne when compared with the reference values. Also, there was no correlation between CRP, and age, total cholesterol, triglyceride, HDL - C, LDL - C,TG / HDL - C. ratio , LDL / HDL - C. ratio , (r = - 0.142, p value = 0,3) (r= - 0.26 , p value = 0.06) ( r = - 0.1, p, value = 0.48) ( r = - 0.21 p value = 0.14) (r = - 0.084 , p value = 0.5) ( r = - 0.17, p value = 0,2) (r = - 0.02 , p value = 0.8) as well as no correlation between age, TC and TG / HDL - C ratio (r = 0.26, p , value = 0.07) (r = - 0.145 , p - value = 0.3), while there were significant positive correlation between LDL - C, LDL / HDL – CR and TG / HDL - c ratio (r = 0.33, p value = 0.018) (r = 0.6 p, value = 0.000) , also there was significant positive correlation between LDL / HDL - c ratio and age ( r = 0.4, p value = 0.004).
Conclusion
Females with acne had normal total cholesterol, Triglycerides, LDL - C, HDL - C, High CRP levels.
