Prakash Somabhai Modi1, Awadhesh Kumar2, Swati Dhirajlal Jethava3, Ruchi Romin Sanghavi4
BACKGROUND
Nosocomial UTI is the most common bacterial infection ranging from asymptomatic bacterial to septicaemia. Gram-negative bacteria contribute 80-85% of UTI and 15-20% by gram positive with major contribution by E. coli. The aim of the study is to assess the bacterial prevalence, drug sensitivity pattern and predisposing factors in nosocomial UTI.
MATERIALS AND METHODS
778 midstream urine samples were tested by conventional methods of which 282 (36.25%) samples were identified as positive for bacteria. All the isolates were subjected to antibiotic sensitivity testing. Statistical analysis was done by Chi-square test.
RESULTS
Bacterial prevalence was 36.25%. 87.95% UTI were caused by gram negative while 12.05% cases were due to gram-positive bacteria. Most prevalent bacterium was E. coli (48.23%). Piperacillin+tazobactam were identified as most sensitive drug for all gram-negative isolates. Among the gram-positive isolates, coagulase-positive bacteria like Staph aureus were sensitive to all tested drugs while coagulase-negative bacteria were less sensitive to all exposed drugs and Enterococcus produced 75% sensitivity rate to vancomycin, teicoplanin and linezolid. UTI was common between 40-60 years (37.23%) with mean age 44.23±20.05 and P value was >0.05. High frequency observed in men (55.32%) than women (44.68%), (P >0.05). 53.19% cases had history of catheterisation (P <0.001).
CONCLUSION
Variable sensitivity pattern and increasing drug resistance observed in uropathogen, so study emphasise over antibiotic sensitivity testing before prescribing empirical therapy, understanding the risk factors helps to contain the UTI.
