Abirbhab Pal1
Lupus is a multisystem disease affecting almost all systems including the
immune system of our body. Its aetiology is not known. Lupus involving kidneys
causes lupus nephritis and adds more complications in the multisystem disease.
Lupus or systemic lupus erythematosus (SLE) is a multifactorial chronic
disease involving multiple systems of the body. It is autoimmune1 in nature.
There is increase in maternal and fetal risk of mortality and morbidity in lupus
with pregnancy.
The rate of pregnancy loss is 1.7 %2 in active SLE during initial first trimester
and the most common adverse morbidity causing factor of fetomaternal side.3
There can be an increase in fetal mortality and morbidity associated with lupus
nephritis.4,5 There is increased risk of intrauterine growth restriction (IUGR) /
neonatal lupus / gestational diabetes mellitus / osteoporosis / HELLP syndrome /
preeclampsia. Associated thyroid disorder is increased with preterm pregnancy.6
