Clinical, Radiological and Laboratory Profile of Covid-19 Patients Admitted to a Dedicated Covid-19 Hospital in Odisha

Abstract

C. Mohan Rao1, Nipa Singh2, Kinshuk Sarbhai3, Saswat Subhankar4 Sanghamitra Pati5, Sidhartha Das6

BACKGROUND
The Covid-19 pandemic caused by severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) is a public health challenge being faced by the world currently.
International and national responses to combat the Covid-19 pandemic have been
very prompt with the setting up of dedicated Covid-19 hospitals. In the state of
Odisha, situated in the eastern part of India, Kalinga Institute of Medical Sciences
(KIMS), set up the first dedicated Covid hospital of the state. This study intends
to chronicle the clinical profile, radiological presentations, laboratory findings, and
clinical outcome of patients admitted to the KIMS Covid hospital.
METHODS
A retrospective analysis of the clinical and laboratory data of patients admitted
with Covid-19 diagnosis at the dedicated Covid-19 hospital from 5th April 2020 to
4th June 2020 was done.
RESULTS
A total number of 272 Covid-19 cases were included in this study. Majority of the
patients were males (83.57 %) and most of the patients (79.04 %) were
asymptomatic. The mortality rate was 1.9 %. Fever (18.38 %), cough (17.27 %),
dyspnoea (16.91 %) and myalgia (14.7 %) were the major symptoms observed.
Severity was mild in 78.94 % cases. Delayed viral clearance was seen in 13 %
cases. The typical features of novel SARS-CoV-2 infection was seen in 12 - 13 %
cases in computed tomography (CT) images of thorax. c-reactive protein (CRP)
was raised as a biomarker of inflammation. Of the 5 deaths encountered, 2 had
diabetes mellitus, 2 were hypertensive and 1 had chronic obstructive pulmonary
disease (COPD).
CONCLUSIONS
Covid-19 may have a delayed viral clearance beyond two weeks. A discordance
between CT images and the clinical condition may also be observed. Diabetes,
hypertension, and high blood CRP levels were significantly associated with
mortality.

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