Shivakumarswamy Udasimath1, Nagesha K.R.2, Kumar Naik H.K.3, Puruhotham R.4
BACKGROUND
Throughout the world, millions of people are affected by corona virus disease 2019
(Covid-19). 16 % of infected Covid-19 people may need hospitalisation. Patients
with severe respiratory or systemic manifestations are at increased risk of venous
thromboembolism. Thrombocytopenia, elevated D-Dimer, prolonged prothrombin
time, and features of disseminated intravascular coagulation laboratory findings
are included in initial reports on Covid-19 patients’ blood samples.
METHODS
This cross-sectional study was conducted at pathology laboratory, Hassan Institute
of Medical Sciences, Hassan, between June 01, 2020 to August 29, 2020. 4096
patients’ blood samples with Covid-19 positivity in Covid Hospital of Hassan
Institute of Medical Sciences, Hassan, were analysed in detail and statistical
reports were derived from the fresh samples for platelet count, prothrombin time
and D-Dimer. The results were compared with severity of infection.
RESULTS
Analysis of 4096 Covid-19 blood sample results, revealed significant abnormal
mean values in critical cases for platelet count in which it was severely decreased
(35,000 cells / cumm), prothrombin time was prolonged for more than 180
seconds and D-Dimer values were 3.74 microgram per ml.
CONCLUSIONS
As the pandemic is spreading, we highlight the importance of laboratory and
clinical findings of coagulation disorders in Covid-19 infected patients. To prevent
death of Covid-19 infected patients, noticing the laboratory findings related to
coagulation will help in early detection of critical patients. This is very important
for relevant treatment and may prevent mortality in Covid-19 infected patients.
