COMPARATIVE STUDY OF DIFFERENT MODALITIES OF TREATMENT IN NEOVASCULAR GLAUCOMA

Abstract

Devi Govindarajan, Kalaiselvi Balasubramanian

BACKGROUND Neovascular Glaucoma is a secondary type of glaucoma caused by a fibro vascular membrane which develops on the surface of iris and the angle. It never occurs as a primary condition, but it is always associated with other abnormalities mostly ischemia. The objectives of the study were- 1. to compare the effect of trabeculectomy with Mitomycin C / ologen implant / glaucoma drainage device surgery in neovascular glaucoma patients. 2. to identify the best method of treatment and 3. to assess the control of intraocular pressure, visual outcome and post-operative complications. MATERIALS AND METHODS 27 Neovascular glaucoma patients attending Department of Ophthalmology, Government Medical College, Omandurar Government Estate, Chennai were evaluated in detail. Of these, randomly 10 patients were treated with Trabeculectomy with Mitomycin C, 10 patients were treated with Trabeculectomy with Ologen implant, 5 patients were treated with Glaucoma drainage device implant surgery. Out of 27 patients 2 patients didn’t turn up for surgery. The control of intraocular pressure, visual outcome, post-operative complications were assessed and compared. RESULTS In this study, out of 25 patients, the mean pre-treatment intra ocular pressure was 45.76 mmHg. Maximum mean reduction of IOP in the first week was seen in group III (drainage implant surgery). But at the end of 12 weeks, all three groups showed statistically significant reduction of mean IOP. There is no significant gross difference between these groups at the end of 12 weeks. CONCLUSION Group I -Trabeculectomy with Mitomycin-C showed more complications compared to other 2 groups; shallow anterior chamber and bleb related complications were more common in group I. Earlier presentation and management of these patients would reduce the dreaded complications of neovascular glaucoma.

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