Naresh Ganpatrao Tirpude1, Sonam Sushilkumar Gupta2
BACKGROUND
To provide postoperative pain relief is a prime duty of health care providers. Failure to relieve pain is morally and ethically unacceptable. Post-operative pain may results in adverse effects such as: a) Physiological Changes: Reduced pulmonary functions, e.g. vital capacity, tidal volume, functional residual capacity; sympathetic stimulation; reduced the physical activity of patients; thereby increasing the risk of venous thrombosis. b) Psychological disturbances: Anger, Resentment, Depression, Adversarial Relationship with Doctors, Insomnia.
Aim of this study was
1. To investigate whether “Postoperative analgesia with Nalbuphine is longer than Pentazocine”.
2. To investigate whether “Side effects/complications are less with Nalbuphine as compared to Pentazocine”.
MATERIALS AND METHODS
It was a prospective randomized double blind observational study. Eighty patients of hydrocoele & inguinal hernia were operated under spinal anaesthesia of age group 20-70 years, ASA grade I & II & patients with controlled co-morbid conditions. In postoperative period, Group N- Inj. Nalbuphine (0.3 mg/kg IM) or Group P- Inj. Pentazocine (0.5 mg/kg IM) was administered to provide postoperative pain relief & to know the duration of pain relief & its side effects.
RESULTS
On statistical analysis, demographic data i.e. age, sex had no influence on outcome of study. Mean VAS score in group N was highly significant (p-value <0.0001) as compared to Pentazocine. Statistically duration of analgesia was highly significant (p-value <0.0001) with longer duration in Group ‘N’ as compared to Group ‘P’. Sedation was more in Nalbuphine group as compared to Pentazocine group. Incidence of nausea and vomiting was more in Pentazocine group as compared to Nalbuphine group.
CONCLUSION
1. Duration of analgesia in Inj. Nalbuphine group was > in Inj. Pentazocine group.
2. Side Effects - Incidence of sedation was more in Nalbuphine group as compared to Pentazocine group. Nausea & Vomiting were more so in Pentazocine group as compared to Nalbuphine group. Limitation of the present study was that sample size was very small.
