Kavita Anand Dhabarde1, Karuna Radhakishan Painjane2, Ashok Hukumchand Madan3
BACKGROUND
Fundus fluorescin angiography (FFA) has been traditional gold standard for
detection of cystoid macular oedema (CME) but nowadays optical coherence
tomography (OCT) is used more often by to detect CME due to various conditions.
Although FFA can assess CME qualitatively, OCT provides quantitative
measurement of foveal thickness. The purpose of this study is to compare
sensitivity of FFA and OCT for detection of CME and know the etiological
distribution of CME and the ability of FFA and OCT in diagnosing CME in different
aetiologies.
METHODS
A hospital based prospective observational diagnostic study was conducted in
tertiary eye care centre in central India on 143 eyes of 103 patients. FFA and OCT
findings in patients of CME diagnosed provisionally on fundus examination were
studied.
RESULTS
Of total 103 patients studied, maximum patients 20 (19.42 %) were in age group
of 55 - 59 years whereas minimum 6 (5.83 %) were in age group of 40 - 44 years.
In 103 patients, 61 (59.22 %) were males and 42 (40.78 %) were females. Both
eyes were involved in 41 (40.78 %) cases. Most common cause of CME was nonproliferative
diabetic retinopathy (NPDR) 52 eyes (35.86 %), followed by branch
retinal vein occlusion (BRVO) 32 eyes (22.06 %), then proliferative diabetic
retinopathy (PDR) 14 eyes (9.6 %), central retinal vein occlusion (CRVO) 13 eyes
(8.96 %). CME on OCT was seen in maximum of retinal vein occlusion patients -
CRVO (84.61 %) and BRVO (84.37 %). Of 145 eyes, 114 (78.32 %) eyes had CME.
CONCLUSIONS
Most common cause of CME was NPDR followed by BRVO, PDR and CRVO.
Sensitivity of OCT in comparison with FFA was 100 % with diagnostic accuracy of
81.38 %. Hence, one can use OCT as first modality investigation for diagnosis of
CME.
