Saroj Patta1, Pradeep Kumar Karem2, Krishna Chaitanya Bevara3, A. Satyanarayana4
BACKGROUND AND AIMS
To study and compare Labetalol and Clonidine as premedication to attenuate haemodynamic changes to Laparoscopy through oral route, as it is safe method of administration and easy to prescribe.
METHODS
In a prospective, comparative randomised study, 60 adult patients of both sexes of ASA Grade I and II were divided randomly into 2 groups of 30 each, Group L and Group C. Group L were given Tab. Labetalol 200mg orally 60-90 minutes before induction. Group C were given Tab. Clonidine 300μg orally 60-90 minutes before induction. We compared the degree of attenuation of haemodynamic changes during laparoscopic surgeries.
RESULTS
Oral Clonidine has better control on the rise in heart rate and mean arterial pressure (MAP) during laryngoscopy for laparoscopy compared to oral Labetalol.
CONCLUSION
We conclude that oral Clonidine showed better attenuation of haemodynamic changes than oral Labetalol.
