Stan Monstrey*
Closure of extensive burn wounds with widely expanded autologous Split-Thickness Skin Grafts (STSG) is associated with undesirable scar formation and contraction, due to the lack of dermis. Various materials for dermal replacement have been developed, either from xenogeneic or allogeneic origin and are placed in the wound underneath a thin STSG in order to improve scar quality. A porcine wound model was used to compare available acellular dermal substitutes with a prototype prepared from glycerol preserved human skin: Glyaderm.
