Gaurav Goyal1 Murtaza A. Chishti2 Kushwath K. K3 Premraj Nagarwal4 Varun Chhabra5 Ajay Meena
Numerous studies suggested that propofol anesthesia is intuitively appealing for its simplicity, stability and safety, permitting the rapid recovery of patients undergoing cardiac surger. However, its use for induction of anesthesia is often results in transient hypotension. The aim of this study was to determine the safety of modified propofol protocol for induction in low ejection fraction cardiac patients undergoing CABG surgery. Fifty patients with ejection fraction between 30% - 60% who were planned for coronary artery bypass graft surgery were included in this study. Patients were divided into two groups of 25 patients each, according to their left ventricular ejection fractions (EF). Group N (EF between 60%-45%) and Group L (EF between 30%-45%). All the patients were given midazolam/fentanyl/vecuronium and propofol for induction according to pre-defined protocol to prevent hypotension and facilitate early intubation. Hemodynamic variables were registered at fixed points. To prevent hemodynamic compromised situation rescue noradrenaline in 5µg/ml aliquots was kept ready. Amount of propofol used, time taken for successful intubation and grading of jaw relaxation was also done
