Niranjan J1 , K. V. Santosh2 , Shashidhar S3 , Shefali H. K4
Congenital cystic adenomatoid malformation (CCAM) is a rare developmental abnormality of the lung previously termed as 'benign hamartoma' or 'dysplastic lung tumor'. It is characterized by abnormal proliferation of tissue resembling terminal bronchioles with cessation of bronchial maturation at the 5 th and 7 th week of development. (1) The lesion is predominantly unilateral, mostly in the left lung and usually involve one lobe. CCAM has a mild male predominance, with an incidence of 1 in 11000(2) to 1 in 35000(3) live births. The exact pathogenesis is unknown; some authors suggest a possible role of over expression of fibroblastic growth factor in the pulmonary mesenchymal cells(2) and others suggest Fatty Acid Binding Protein (FABP 7) under expression in the fetal lung. (4)
