CORRELATION STUDY BETWEEN SERUM PROSTATE SPECIFIC ANTIGEN AND BODY MASS INDEX

Abstract

Rajan S. P 1 , Santhosh V 2 , Nimisha Vinod 3

AIM To study the correlation between body mass index and Serum Prostate Specific Antigen (PSA) in a tertiary care hospital in Palakkad, Kerala. MATERIALS AND METHODS Men aged 30-85 years old were selected randomly with no history of prostate cancer. Data regarding age were taken along with measurements of weight and height using which BMI was calculated. PSA was measured at the central laboratory using Paramagnetic particle chemiluminescence immunoassay. Data were analysed using SPSS version 17.0 and reported as means±SD for continuous variables. Student’s t-test and ANOVA were used to compare continuous variables and categorical variables respectively. RESULTS After screening for prostate cancer, 100 subjects were included in the study. Mean age was 56.7±18.7 (Range 30 to 85) years; mean BMI was 26.5±3.5 kg/m2 , and mean PSA was 2.45±1.23 ng/mL. Using BMI, participants were classified as 28% in the normal range, 55% as overweight, and 17% as obese. No significant difference in age was observed between BMI groups across age groups. CONCLUSIONS This study found an inverse relation between Prostate specific antigen and body mass index. Hence, care should be taken when interpreting the results of the same based on BMI of the patient concerned

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