DEXMEDETOMIDINE AS AN ADJUVANT WITH 0.25% BUPIVACAINE FOR SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK

Abstract

Prakash R. Dhumal1, Padmanabha D. V2, Priyanka Rathi3, Bhagya D. V4, Nilesh Jawe5

BACKGROUND
The aim of this study is to evaluate the effect of addition of dexmedetomidine to 0.25% bupivacaine in brachial plexus block.
MATERIALS AND METHODS
80 consenting patients fulfilling the inclusion criteria were divided randomly into two groups using “slips in a box technique” of 40 each. Group D (study group)- 30 mL of 0.25% bupivacaine with 0.5 mL (50 μg) dexmedetomidine. Group B (control group)- 30 mL of 0.25% bupivacaine with 0.5 mL, 0.9% saline. Neural localisation was achieved using a nerve stimulator. All the patients received brachial plexus block through the supraclavicular approach by an experienced anaesthesiologist different from the one assessing the patient intra and postoperatively. Both were blinded to the treatment groups. Sensory block was assessed by pinprick test using 3-point scale. Motor blockade was assessed using Bromage 3-point score. Onset of sensory and motor block, duration of sensory and motor block, duration of analgesia and quality of block was noted.
RESULTS
There were no significant differences in demographic and haemodynamic data. Onset of sensory block was faster in Group D (12.33±1.64 mins.) compared to Group B (21.78±2.22 mins.). Onset of motor block was faster in Group D (9.38±1.55 mins.) compared to Group B (15.68±2.09 mins.). Duration of sensory block in Group D showed 508.50±33.25 mins. and Group B 219.38±24.42 mins. Duration of motor block in Group D showed 434.25±33.96 mins. and Group B 165.75±19.20 mins. Duration of analgesia in group D was 538.50±33.25 mins. compared to group B with 264.38±24.42 mins. Quality of block was better in Group D as compared to Group B.
CONCLUSION
Dexmedetomidine at the dose of 50 μg added to 0.25% bupivacaine in supraclavicular brachial plexus block in upper limb surgeries is highly effective in prolongation of motor and sensory analgesia and provides better postoperative analgesia without any potential side effects.

image