EFFECT OF ORAL CLONIDINE PREMEDICATION ON HAEMODYNAMIC CHANGES DURING LAPAROSCOPIC CHOLECYSTECTOMY - A CLINICAL STUDY

Abstract

Abu Lais Mustaque Ahmed1, Hirok Roy2

BACKGROUND
Laparoscopic surgeries are the recent advances in the field of surgery and are the essence of today’s surgical practice. Laparoscopic cholecystectomy has revolutionised gall bladder surgeries and has become the treatment of choice for cholelithiasis. This procedure has minimised the numbers of open cholecystectomy performed these days.
AIMS AND OBJECTIVES
To study the effect of oral clonidine premedication on haemodynamic changes during laparoscopic cholecystectomy.
MATERIALS & METHODS
The present study was conducted in the Department of Anaesthesiology of Assam Medical College, Dibrugarh for a period of one year from July 2012 to June 2013 on patients undergoing laparoscopic cholecystectomy at operation theatre of Department of General Surgery of Assam Medical College and Hospital, Dibrugarh. A total of 150 adult patients of either sex between the age group of 18 to 40 years of ASA-1 and ASA-2 undergoing elective laparoscopic cholecystectomy were divided randomly into two groups of 75 patients each.
RESULTS
With the present study that oral premedication with Tab. Clonidine 150 mcg administered 90 minutes before surgery was able to prevent adverse haemodynamic changes during elective laparoscopic cholecystectomy under general anaesthesia.
CONCLUSION
Hence, from the findings of this study, we can reasonably recommend oral premedication with Tab. Clonidine 150 mcg in otherwise healthy patients undergoing laparoscopic cholecystectomy.

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