Kamlesh Kumar Gupta 1 , Shyam Chand Chaudhary 2 , Surendra Kumar Khunte 3 , Kamal Kumar Sawlani 4 , Arvind Kumar Mishra 5 , Vivek Kumar 6 , Virendra Atam7 , Satyendra Kumar Sonkar
Vitamin D deficiency and osteoporosis is a common extra pulmonary manifestation in COPD patients. Evidence suggests that the prevalence of osteoporosis in patients with COPD is high and potentially important with disease progression. AIM- The aim of this study was to estimate the serum Vitamin D levels in a well-defined cohort of patients with COPD and to correlate stages of COPD with Vitamin D level. MATERIAL AND METHODS It is a case control study, done over a period of 1 year in a tertiary care centre in North India. The study group was consisting of 60 male & female COPD patients diagnosed by spirometry and severity was determined according to GOLD classification criteria as well as age and sex matched 60 healthy controls. RESULTS Vitamin D level was found to be lower in cases as compared to controls and deficiency was more severe in higher stages of COPD (p<0.001). CONCLUSION Vitamin D deficiency correlated well with severity of COPD. Therefore, an early intervention with vitamin D supplementation might play a significant role in decreasing the comorbidity of COPD.
