Kallol Bhattacharjee, Dwijen Das, Abu Nasar Mohd. Masroor, Chandra Prakash Thakur
BACKGROUND Acute kidney injury (AKI) is characterised by sudden impairment of kidney function resulting in the retention of nitrogenous and other waste products normally cleared by the kidneys as well as impairment of acid-base balance, and water homeostasis. AKI is not a single disease but, rather, a designation for a heterogeneous group of conditions that share common diagnostic features. When this impairment is prolonged, erythropoietin secretion by this organ is decreased and toxic metabolites accumulate and cause haematological changes including decrease in Hb, HCT, MCH, MCV, RBC and platelet counts. This study evaluates haematological profile in patients with acute kidney injury. MATERIALS AND METHODS This study was conducted on 100 patients with acute renal impairment and equal number of age and sex matched healthy individuals. Initially patients with renal impairment were tested and after confirmation of AKI, complete blood count was performed for each patient and compared with control group and finally obtained data were analysed. RESULTS Comparison between patients with AKI and controls revealed that there is significant haematological changes (RBC, HCT, Hb and MCHC) in case group in comparison with control group. CONCLUSION It was inferred that AKI results not only in anaemia but also a number of other haematological abnormalities and is a new field for future researches as there is a dearth of literature in this arena.
