Histopathological Analysis of Neoplastic and Non Neoplastic Lesions of Salivary Gland â?? A Retrospective Study in a Tertiary Care Hospital

Abstract

Sheela K.M.1, Priya V.S.2, Lali K. Rajan3, Ashida M. Krishnan4

BACKGROUND
Salivary gland lesions constitute less than 1 % of tumours and about 4 % of all
epithelial neoplasms of head and neck region. These comprise of a wide variety of
benign, malignant and non-neoplastic lesions which exhibits a difference in
histological behaviour. There are no reliable criteria to differentiate on clinical
grounds the benign from malignant ones. So morphological evaluation is
necessary. We aim to study the frequency of various salivary gland lesions in
sialoadenectomy specimens and categorise them into neoplastic and nonneoplastic
lesions.
METHODS
It is a record based retrospective 5-year study carried out in the Government
Medical College, Thiruvananthapuram, Kerala, from January 2014 to December
2018.
RESULTS
In this study a total of 329 histopathologically proven cases of salivary gland
lesions were included. Neoplastic lesions and non-neoplastic lesions constituted
78.42 % and 21.58 % respectively. Pleomorphic adenoma was the most common
neoplasm (50.54 %) trailed by Warthin’s tumour (9.73 %). Most common
malignant neoplasm encountered in our study was mucoepidermoid carcinoma
(9.73 %) among which low grade tumours showed predominance. We observed
significantly higher incidence of benign and malignant lesions in the 5th to 6th
decade while non neoplastic lesions were seen more in the 4th to 5th decade.
Average age of the patients with salivary gland tumours was 46.12 ï?± SD 15.57.
Majority of cases of salivary gland lesions in our study were from parotid gland
(75.68 %) followed by submandibular gland 24.01 %.
CONCLUSIONS
Pleomorphic adenoma was the most common benign tumour in our study and
mucoepidermoid carcinoma the most common malignant tumour. Neoplastic
lesions showed a predominance over non neoplastic lesions. Histopathological
examination is the mainstay for diagnosis and clinical management.

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