Dharmakanta Kumbhakar1, Partha Pratim Talukdar2
BACKGROUND
The breast tissue consists of both specialised epithelial cells and stroma. It is a
site of a broad array of pathological alterations. Both benign and malignant lesions
can occur in the breast. Breast cancer is the most commonly diagnosed female
cancer accounting for 20 % of female malignancies globally.
METHODS
The study was carried out to evaluate the histopathological patterns of 589 breast
lesions whose biopsied breast tissues were presented at the Pathology department
of Tezpur Medical College and Hospital, Tezpur, Assam, for a period of three (03)
years from January 01, 2017 to December 31, 2019.
RESULTS
Out of 589 cases of breast lesions, 418 were benign breast lesions (70.97 %) and
171 were malignant (29.03 %) with a benign and malignant ratio of 2.44:1.
Fibroadenoma breast was the most common benign breast disease were 264 out
of 418 (63.15 %) and infiltrating duct carcinoma was the commonest malignant
breast lesions, in this study there were 123 out of 171 (71.93 %). Among 123
cases of infiltrating duct carcinoma, 93 (75.61 %) were grade III ;27 (21.95 %)
were grade II and 03 (2.44 %) were grade I as per Nottingham histologic score
system in the study group. Metastatic lymph nodes were 89 (52.05 %) were seen
in the malignant cases. Early presentation (stage 0, I and II) constituted 77 (45.45
%) while late presentation (stage III and VI) accounted for 94 (54.97 %) in the
breast malignancy in the study.
CONCLUSIONS
Histopathological study plays very important role in the diagnosis, treatment and
prognosis of breast lesions. This study highlighted the distinct incidences and
pathological characteristics of wide range of breast diseases and affirmed that
breast cancers in developing countries like India are characterised by late
presentation.
