Rajendra Prasad Jagannadham1, Lakshmi Latchupatula2, Sravani Ponnada3, Neelima Lalam4, Raghunadhababu Gudipudi5, Bhagyalakshmi Atla6c
BACKGROUND
A variety of non - neoplastic and neoplastic conditions involve the nasal cavity,
paranasal sinuses and nasopharynx and these are very common lesions
encountered in clinical practice. Histopathological examination of these lesions is
the gold standard for diagnosis because management and prognosis vary among
different lesions. The aim of the present study was to evaluate the
histopathological study of the lesions of the nasal cavity, paranasal sinuses and
nasopharynx in relation to their incidence, age, gender and site wise distribution
and to compare the results with the available data.
METHODS
A study of 88 cases was conducted for a period of 2 years from August 2017 to
July 2019. After fixation, Processing and Haematoxylin and Eosin staining and
special stains histopathological diagnosis was made.
RESULTS
Among 88 total cases, 58 were males and 30 were females. A male predominance
was observed with a male to female ratio of 1.93 : 1. They were more common in
third, fourth and fifth decade of life. Malignant nasal lesions were seen after fourth
decade of life. Nasal lesions were more common in nasal cavity (67.05 %),
followed by paranasal sinuses (18.18 %) and nasopharynx (14.75). Out of 88 total
cases, 39 (44.32 %) were non - neoplastic, 30 (34.09 %) were benign and 19
(21.59 %) were malignant nasal lesions.
CONCLUSIONS
Sinonasal lesions and nasopharyngeal lesions can have various differential
diagnoses. A complete clinical, radiological and histopathological correlation helps
to categorize these sinonasal lesions into various non - neoplastic and neoplastic
types. But histopathological examination remains the mainstay of definitive
diagnosis.
