Shrirang Kishor Bhurchandi, Anjalee Chiwhane, Sunil Kumar, Pradeep Dattatray Jalgaonkar, Sunayana Sahebrao Lomte
BACKGROUND
It is observed that anaemia is a common problem in patients hospitalised for acute coronary syndromes. There have been reports in worldwide studies of an association between anaemia and poor prognosis in patients with Acute Coronary Syndromes (ACS).
MATERIALS AND METHODS
All consecutive patients having ST-elevation myocardial infarction, non-ST elevation myocardial infarction and unstable angina who were admitted in medicine ward, Medicine Intensive Care Unit (MICU), Cardiology Department (CRD), Cardiovascular and Thoracic Surgery (CVTS) Department and incidentally found in other departments of Acharya Vinoba Bhave Rural Hospital admitted from 1st November 2014 to 31st December 2015 at AVBRH. Total 200 patients were included in the study.
RESULTS
Our study showed an association between haemoglobin levels and mean age (p=0.0001), gender (p=0.0001), risk factors like smoking (p=0.035), tobacco (p=0.001) and Killip’s class I (p=0.0001), III (p=0.0001) and IV (p=0.0001). On distribution of the MACE’s during hospital stay stratified with Hb levels, the results of analysis by Chi-square test showed that there were statistically significant differences at various haemoglobin levels in MACE’s as post-infarction angina, heart failure, VT/VF and death (p<0.05 for all). On distribution of the MACE’s during follow up on 30th day and on 180th day stratified with Hb levels, the results of analysis by Chi-square test showed that there were statistically significant differences at various haemoglobin levels in MACE’s as post-infarction angina, re-infarction, heart failure, VT/VF and death (p<0.05 for all).
CONCLUSION
To conclude our study results, it was found during the study that anaemia as an important risk factor was strongly associated with major adverse outcomes in patients with ACS. Our study suggested that there was a statistically significant correlation between the low Hb levels and MACE’s (post-infarction angina, re-infarction, heart failure, VT/VF and death) over the study period with p values <0.05 for all the outcomes. Our study results concluded that anaemia was a strong risk factor for major outcomes and increasing severity of anaemia had correlation with MACES in ACS.
