Dr. Jinendra Mohan Jain
BACKGROUND Poisoning with organophosphorus compounds is one of the commonest forms of poisoning in our country. Patients with organophosphorus poisoning present with symptoms and signs of acetyl choline excess which is called as acute cholinergic crisis. Type II paralysis or intermediate syndrome (IS) is one of them. We wanted to study the clinical profile of patients of OPP, with a special reference to the neurological aspect of OPP, especially the intermediate syndrome. METHODS This study was conducted among 100 patients in the rural region, where the incidence of poisoning with OPCs is very high. RESULTS Most common poisoning was found to be organophosphorus compound (72%) 100 out of 140 patients, and higher incidence reported in age group (12 to 40 years). Maximum incidence of intermediate syndrome was seen in poisoning with Parathion (75%) followed by dimethoate poisoning with an incidence of 45.3%. The overall incidence of Intermediate syndrome in present study was 37%. CONCLUSIONS Insecticide poisoning was associated with wide clinical features ranging from vomiting, miosis to convulsions and intermediate syndrome. No correlation was found between dose ingested and clinical severity. But clinical severity did depend upon, to certain extent, the delay in admission.
