H. Lakshmi Vasavi1, E. Kiran Kumar2
Intestinal neuronal dysplasia (IND) is one of the conditions known to mimic Hirschsprung’s disease (HD) both clinically and radiologically, and clinically presents with intestinal obstruction in pediatric age group. Two types are described.1 IND Type A is characterized by a malformation of the adrenergic nerve supply to the blood vessels and IND Type B, in which the submucosal plexus is involved. Giant ganglia are involved in Type B, and there is abnormal morphology of the nerve cell groups and nerve cell fibres.2 In the present case, diagnosis was established mainly by biopsy and microscopic examination of H&E stained sections, which show increased ganglion cells both in number and size, and confirmed by Cathepsin D immunostaining.
