Prathima Raj Dara1, Rajendra Prasad Suram
AIM
To study the lipid profile in ART treated and untreated patients of HIV positive cases.
MATERIALS AND METHODS
In this study, the patients were divided into HIV seropositive cases (n=74) and healthy non-HIV patients were selected as controls (n=45).
INCLUSION CRITERIA
HIV infected ART treated subjects who were a minimum of three months on medication (<350 cells/cu mm, n=37) and ART untreated patients (>350 cells/cu mm, n=37) were newly diagnosed. Control group was selected of healthy HIV seronegative, non-smokers.
EXCLUSION CRITERIA
Subjects who had hypertension, diabetes mellitus, obesity, alcohol abusers, smokers, and patients who were on multivitamin, antioxidant supplements, and hyperlipidaemic drugs were excluded.
RESULTS
This study consisted of 37 HIV positive ART treated patients, 37 HIV positive ART untreated patients, and 45 healthy seronegative non-HIV patients. The mean CD4 count in HIV ART untreated subjects was 168.33±2.9 and after three months of treatment, the mean CD4 count was 250.39±1.7. It was observed that in ART untreated patients, total cholesterol, HDL, and LDL cholesterol was less when compared to controls. In ART treated HIV patients, males were having more total cholesterol, triacylglycerols, and LDL cholesterol when compared to females. In ART untreated HIV patients, males were having more total cholesterol, triacylglycerols, and LDL cholesterol when compared to females.
CONCLUSION
When ART treated or untreated are carefully prescribe an anti-retroviral treatment regime, which will undeniably support in supervision of dyslipidaemia in HIV seropositive patients infected with HIV were constantly screened for lipid abnormalities.
