Dr. Asit Chandra Roy
BACKGROUND Japanese Encephalitis (JE) caused by Flavivirus is the most common cause of endemic encephalitis. It usually affects the children and is a life-threatening disease having high morbidity and mortality. The aim of the study was to identify the pattern of involvement of brain in confirmed cases of Japanese encephalitis. MATERIALS AND METHODS We had done an institution based observational study in our Dept. of Radio-diagnosis, NBMC & H. 19 children suffering from Japanese encephalitis confirmed by IgM ELISA underwent MRI of Brain and frequency of involvement of different sites of brain was evaluated. RESULTS Based on characteristic MRI findings, different areas of brain involved were bilateral thalami, basal ganglia, cerebellum, brainstem, temporal lobe etc. of which thalamic involvement (84%) was most common. CONCLUSION After the data collection, we have come to a conclusion that among the different sites of brain involved in JE, thalamus is most frequently involved.
