Suresh Bendwal
BACKGROUND
Nonalcoholic Fatty Liver Disease (NAFLD) is a common liver disorder closely associated with insulin resistance and Type 2 Diabetes Mellitus (T2DM) and also diabetic patients appear to have an increased risk of developing NAFLD than nondiabetic subjects and certainly have a higher risk of developing fibrosis and cirrhosis. The aim of present study was to find out the prevalence of NAFLD in patients of T2DM and its correlation with HbA1c level, body mass index and age.
MATERIALS AND METHODS
300 patients of T2DM were included in this study. All patients didn’t have any liver disease and all were nonalcoholic. Ultrasonographic evaluation done in all patients to diagnose NAFLD and its correlation seen with HbA1c level and other parameters.
RESULTS
48% patients (144 out of 300) were found to be having NAFLD in ultrasonographic study. Mean HbA1c level of the patients with NAFLD was higher than patients with normal USG findings (9.4% vs. 6.5%). 72.4% of patients with BMI of 30-39.9 kg/m2 had NAFLD followed by 58.9% of patients with BMI range from 25-29.9 kg/m2 had NAFLD and 38.07% with BMI range of 18.5-24.9 kg/m2 had NAFLD.
CONCLUSION
The present study showed higher prevalence of NAFLD in diabetic patients with its significant association with HbA1c level and BMI. The prevalence of NAFLD increased in uncontrolled diabetic (high HbA1c) and obese (high BMI) patients.
