Abhishek Gupta, Ketaki Utpat, Unnati Desai, Jyotsna M. Joshi
Pseudomesotheliomatous adenocarcinoma is a variant of peripheral lung carcinoma that is characterized by extensive invasion of pleura which closely resembles malignant pleural mesothelioma clinically and anatomically. Radiologically, it is distinguished by Leung’s criteria. It most commonly emanates from an adenocarcinoma; however other types of lung carcinomas may also precipitate it. Its elucidation in the literature is very limited. Although the distinct clinical and histopathological features of this entity have been described since a long time, its recognition as a distinct variety of lung carcinoma has remained small fry. Little is known of its incidence and only sporadic cases have been reported until now. We present an intriguing case of this rarefied entity. This middle-aged woman was initially speculated to have Rheumatoid arthritis associated pleural effusion which later on turned out to be metastatic adenocarcinoma, positive for both Thyroid Transcription Factor-1 (TTF-1) and Napsin A. The diagnosis could be consummated with a blind closed needle biopsy of the pleura.
