QUANTIFICATION OF PROTEINURIA IN PRE ECLAMPSIA USING PROTEIN AND CREATININE RATIO IN RANDOM URINE SPECIMEN

Abstract

R. Padmaja1, M. L. Rajeshwari2, Swetha3

Hypertensive disorders complicating pregnancy are common and form one of the deadly triad along with haemorrhage and infection that results in much of the maternal morbidity and mortality related to pregnancy. Proteinuria is essential for the diagnosis of preeclampsia. As the Proteinuria increases, the likelihood of complications also increases and hence a rapid and accurate detection and quantization of Proteinuria is essential for the management of hypertensive pregnant women. The protein creatinine ratio in a single urine specimen has been used for the rapid and accurate detection of proteinuria in hypertensive pregnant women as it avoids collection errors and gives physiologically more relevant information.

OBJECTIVES OF THE STUDY: To study the clinical profile of preeclampsia patients. To assess the degree of Proteinuria by 24 hour urine protein and spot urine protein Creatinine ratio in the study population To study if the spot urine protein and creatinine ratio will provide accurate quantification of proteinuria in hypertensive pregnant women.

MATERIALS AND METHODS: This was observational study it was conducted in King George Hospital for a period of one year & 60 patients were included for the study.

RESULTS: In the present study: spot urine p/c ratio sensitivity 100%, specificity 66.67%, and positive predictive value of 98.27% added.

CONCLUSION: quantization of proteinuria, when properly interpreted, can provide valuable information.

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