Rupali Bose1, Pushpa Varma2, Vinod Kumar Baranwal3, Smita Sinha4
BACKGROUND
Penetrating Keratoplasty (PK) has been one of the most effective and successful organ transplants for over a decade with Post-PK glaucoma, a significant clinical problem because of its frequency of occurrence, difficulty in diagnosis and monitoring and complexity of management leading to irreversible visual loss and graft failure.
MATERIALS AND METHODS
A prospective study conducted over 2 years. 67 cases of penetrating keratoplasty were followed postoperatively for raised intraocular pressure.
RESULTS
We found the incidence of postoperative glaucoma to be 25.4%. Occurrence varied with indication for PK. Statistical significance was obtained when PK was combined with other surgical procedures (p=0.003). There was no difference in interval estimate of postoperative outcome, but 82% of eyes with postoperative elevated Intraocular Pressure (IOP) were found to have graft failure with p value 0.001.
CONCLUSION
The incidence of glaucoma after penetrating keratoplasty is high especially if additional procedures taken at same sitting and results in significant graft failure rates.