RAISED INTRAOCULAR PRESSURE AFTER PENETRATING KERATOPLASTY- HOW UGLY IS THE PROBLEM?

Abstract

Rupali Bose1, Pushpa Varma2, Vinod Kumar Baranwal3, Smita Sinha4

BACKGROUND
Penetrating Keratoplasty (PK) has been one of the most effective and successful organ transplants for over a decade with Post-PK glaucoma, a significant clinical problem because of its frequency of occurrence, difficulty in diagnosis and monitoring and complexity of management leading to irreversible visual loss and graft failure.
MATERIALS AND METHODS
A prospective study conducted over 2 years. 67 cases of penetrating keratoplasty were followed postoperatively for raised intraocular pressure.
RESULTS
We found the incidence of postoperative glaucoma to be 25.4%. Occurrence varied with indication for PK. Statistical significance was obtained when PK was combined with other surgical procedures (p=0.003). There was no difference in interval estimate of postoperative outcome, but 82% of eyes with postoperative elevated Intraocular Pressure (IOP) were found to have graft failure with p value 0.001.
CONCLUSION
The incidence of glaucoma after penetrating keratoplasty is high especially if additional procedures taken at same sitting and results in significant graft failure rates.

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