Shreyansh Talera1, Saurabh Singhal2, Nishant Wadhera3, Mayank Arora4, Ravi Pratap5
BACKGROUND
WHO has declared Coronavirus disease 2019 (Covid-19) as a pandemic. Covid-19
leads to sickness and death. Human serum albumin (HSA) is the most common
circulating protein in the body having oncotic as well as non-oncotic properties.
The role of albumin in death among Covid-19 subjects, especially in this part of
the country has not been frequently reported. The aim of the study was to analyse
the role of serum albumin level as prognostic marker for Covid-19 positive patients.
METHODS
The present study was conducted in the department of Medicine at Chhatrapati
Shivaji Subharti Hospital, Subharti Medical College, Meerut, UP. The study
comprised of 100 subjects who were Covid positive from May 2020 to July 2020.
A detailed explanation was given to all the participating respondents regarding the
study and their contribution to it. Covid-19 was diagnosed on the basis of the WHO
interim guidelines. A questionnaire was prepared to collect the patients’
demographic profile. Patients date of admission and discharge was recorded along
with the outcome i.e., whether patient expired or survived. Patients’ diagnosis was
identified along with the comorbidity (if present). Laboratory investigations
comprised of CBC and serum albumin detection. Data so collected was tabulated
in an excel sheet, under the guidance of statistician. Collected data was analysed
using Statistical Package for the Social Sciences (SPSS) software version 24 and
the tests used were t test and Fisher’s exact test and the level of significance was
set at p < 0.05.
RESULTS
The study comprised of 100 subjects, out of which 45 were males and 55 were
females. The overall mean age of the study subjects was 37.52 years. In our study,
mortality was 35.29 %, 9.33 % and 85.7 % of the subjects having Covid-19+ type
2 diabetes (T2DM), only Covid-19 and Covid-19+ hypertension respectively with
statistically significant difference as p < 0.05. Albumin level was significantly lower
in expired patients (2.99) as compared to survivors (3.85) as p < 0.05. Hospital
stay was also higher in expired patients.
CONCLUSIONS
Covid-19 patients had low serum albumin levels and that might play a role in the
survival of patient.
