SIGNIFICANCE OF LOWERING SERUM URIC ACID LEVEL IN HYPERTENSIVE PATIENTS

Abstract

Manabendra Nayak

BACKGROUND Worldwide, hypertension is an important public health challenge because of its high frequency and concomitant risk of coronary heart disease, stroke, kidney disease and other vascular complications. Interestingly, serum uric acid can have relation with hypertension (HTN), stroke, dyslipidaemia, diabetes mellitus and obesity. This led many people to get involved in the study to find out the exact correlation between hyperuricemia and hypertension. MATERIALS AND METHODS It was a hospital based, time bound, case control study done in the Department of Medicine, Down Town hospital, Guwahati, Assam. All patients diagnosed with hypertension in the period of November 2014 to October 2015 were studied; 50 patients of hypertension were taken as study cases and 50 normal OPD patients were taken as control for comparison. Serum uric acid level was compared between non-hypertensive and hypertensive group and statistical analysis was done by using Microsoft Word, Excel 2007 software. RESULTS A total of 100 persons of age >18 years having hypertension were studied; 50 persons were in hypertensive group and 50 persons were in control group. Serum uric acid level of more than 6.8 mg/dl was considered significant. Hyperuricemia among hypertensive pts. was most prevalent in 41-60 yrs. age group (43.75%). There was no significant difference in prevalence of hyperuricemia among hypertensive male (35.29%) and female (37.50%) pts. CONCLUSION The prevalence of hyperuricemia is significantly higher in 40 to 60 years age group and not very significant difference between male and female. With the increase in duration of age (>60 years) hyperuricemia is less responsible for hypertension.

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