Mamtha G, Prerna Malhotra , Shruti B. N , Pravin G. U
We are presenting two cases of Sirenomelia. It derives its name by its resemblance to the Mermaid (Siren) of Greek mythology and called as Mermaid syndrome. It is a rare congenital anomaly which presents with variable degree of fusion of lower limbs, sacral and pelvic bony anomalies, absence of external genitalia, imperforate anus and renal agenesis or dysgenesis. There are approximately 300 cases reported in the literature, 15% of which are associated with twinning, most often monozygotic. Caudal Regression Syndrome is thought to be the result of injury to the caudal mesoderm early in gestation. Agenesis of left kidney was found in one of our cases on autopsy.